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    Detectors

    Chromatography Gels

                                                  Material Safety Data Sheet: Coated Silica

    Chemical names and synonyms:       Silica gel; silicon dioxide.

    Uses:               Coated silica is intended for packing columns for use in chromatography.

    Composition:     Amorphous silica with polymeric coatings.

    Chief hazard:     Inhalation. Avoid inhaling products containing microparticulate amorphous silica; it dries and irritates                       mucous membranes and respiratory passages. Elevated exposure over long term can lead to silicosis.                       The occupationalexposure standard for amorphous silica is as follows:

                                                         8 hr TWA ref period                    10 min TWA ref period

                          Total inhalation dust            6mg/m3                                        ---

                          Respirable dust                   3mg/m3                                        ---

    Handling:          To avoid inhaling, handle material in a fume hood. Follow Good Laboratory Practices.

    Fire Hazard:       Silica is not a fire hazard. The polymeric coatings could burn briefly; avoid breathing any resulting                       gases.

    Reactivity:         No hazards known.

    Spill Clean-up:   Use a vacuum cleaner if available. If not, sweep up using respiratory protection. May be discarded in a                       landfill.

    First aid:          Eyes: Irrigate with water to remove particles.

                         Skin: Silica tends to dry skin; wash with soap and water.

                         Inhalation: Blow nose to expel particles.

                         Ingestion: Spit out and wash mouth with water.

                         If irritation persists, consult a physician.

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